S2: Biomedical Technologies

Coordinator:

S2: Biomedical Technologies

by Coordinator:
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Theme: Biomedical technologies for improved therapeutics and healthcare.

Biomedical technology has advanced markedly over the past few decades that supported the development of therapeutics, processes, and services enabling the delivery of high-quality healthcare, mostly to richer communities of the developed countries. Developing countries, on the other hand, are facing severe resource limitations including sophisticated infrastructures and technical expertise and therefore, they are compelled either to seek medical treatments abroad or import the advanced technologies that often lack experts. Nevertheless, developing countries are also trying to develop modern biomedical technologies and services that would improve the quality of healthcare of their communities.
Among several reasons, gaps in knowledge and skills for effective research and innovation represent the most important factors that limit the biomedical research and development in developing countries. This symposium aims to provide a platform for updating and exchanging state-of-the-art knowledge on biomedical science and technology and link them to the development of therapeutics, medical devices and diagnostics in the field of neuroscience, immunology, immunotherapy and tumor biology, etc. Cost effective technologies based on innovative ideas and suitable for developing economies will be given high priority.

Objective of the Symposium
Biomedical technology is the application of engineering and technology principles to the domain of living or biological systems, with an emphasis on human health and diseases. This symposium will bridge the gap between recent scientific development in biomedical science and the technologies developed for speeding up of medical application, the knowledge from different areas of technology to advance the therapeutic treatments of various diseases. The technology with innovative idea to compensate the cost-effective way such as Jack Andraka who developed a crucial earlier detection of pancreatic cancer are more welcoming.
Many technologies have been developed to make the healthcare better; however, these technologies are cherished based on their reality ground, the potential impact to community and the wide accessibility by many populations. This symposium will bring together experts in oncology, immunology, biomedical engineering, genetics and computational biology to discuss the current scientific discoveries and the challenges in the field of public health and medical services currently faced by developing countries like ours.

The symposium includes, not limited to, the following topics:

  • Advances in the development of diagnostics and therapeutics using rapid and cost-effective methods.
  • Biomedical applications of natural resources. Technologies that use the natural resources to facilitate medical care eg. Use of solar power for medical devices.
  • 3Rs (Replacement, Reduction and Refinement) in biomedical research. Replacing animal experiments with biomaterials eg. Synthetic skin samples, 3D printed liver.
  • Importance of genetics, molecular and cell biology in biomedical research. Gene editing/genome engineering/protein engineering technology to develop DNA and protein therapeutics to cure the unmet demand.
  • Epidemiological disease investigation, management and control
  • Biomedical informatics and computational biology for substantial innovation in healthcare

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Coordinator:

Dr. Devi B. Basnet has been working for more than14 years as a senior scientist for a global biopharmaceutical company namely Medytox, Inc. He also got postdoctoral training at Ewha Woman University from 2006 to 2008 after his graduation in 2005. He has a dozen of national and international journals publication in his field of research. His main interest and research field is on genetic engineering and protein therapeutics development including antibody production and processing. He has good teaching experience in various colleges in Nepal after his master in organic chemistry from Tribhuwan University. He has a keen interest in the initiation and running of various projects for the welfare of the public and developing a various research institute in Nepal. He was the founder vice-president of SONSIK and NRNA-South Korea. He served as a national coordinator of NRNA-South Korea and then served as NRNA-ICC representative from South Korea for two tenures and currently, he is also the NRNA-ICC South Korea representative. He was the board of directors and then current president of BRICK Investment Pvt. Nepal. He was the Board of directors of RIBB (Research Institute of Bioscience and Biotechnology) and currently involved in various research activity of RIBB. He worked as the initiation of Open University initiated by NRNA in the past and played the important role in SKI committee and initiation of the first global knowledge convention in2018.Currently, he is member of steering committee of 2ndNRNAGlobalKnowledge convention and coordinator of First NRNA Asia-Pacific knowledge convention.


Invited Speakers:

Dr Ramesh Giri was born in Chitwan, Nepal and graduated with distinction from Tribhuvan University (Nepal) with an MSc in Organic Chemistry in 1998 under the supervision of Prof. S. M. Tuladhar. As a Shell Centenary Scholar, he received his MPhil in Bioorganic Chemistry in 2003 with Prof. J. B. Spencer from the University of Cambridge (UK) where he studied biochemical processes of antibiotic synthesis. He earned his PhD in Chemistry from The Scripps Research Institute in 2009 with Prof. Jin-Quan Yu working on the development of novel chemical technologies for pharmaceuticals. As a postdoctoral fellow in the research laboratory of Prof. John F. Hartwig at the University of California, Berkeley and the University of Illinois Ubana-Champaign, he conducted mechanistic studies on key chemical technologies for pharmaceuticals. In 2012, he joined the faculty of the Department of Chemistry and Chemical Biology at the University of New Mexico as an Assistant Professor and was promoted to Associate Professor with tenure in 2018. In 2019, Prof. Giri moved to The Pennsylvania State University as a named professor holding the Weinreb Early Career Professorship. Prof. Giri’s research group is focused on developing and understanding sustainable chemical processes for the manufacturing of pharmaceuticals. Prof. Giri has received Cambridge Overseas Trust Scholarship from the University of Cambridge (UK), Monbukagakusho:MEXT from the Tokyo Institute of Technology (TIT) (Japan)(declined to accept Cambridge Overseas Trust Scholarship), Myron Rosenblum Endowed Fellowship (Brandeis University, US), Outstanding Teaching Fellow Award (Brandeis University, US), Research Allocation Grant (UNM, US), Nepal Academy of Science and Technology Research Award, Theme Chemistry Journals Award, US National Science Foundation (NSF) CAREER Award, and US National Institute of Health (NIH) MIRA Award.


Dr Deepak Upreti

Summary

  • Experienced Immunologist with expertise in cancer immunology. Actively involved in designing and testing the efficacy of Immunotherapy product CART, NK cells and oncolytic virus for clinical development.

Education

  • PhD in Immunology (2011-2017), University of Manitoba, PhD research project was entitled, “Understanding Immunosuppression in Head and Neck Cancer Patients: Validation of prognostic markers and development of NK based immunotherapy.”
  • Undergraduate: B.Tech in Biotechnology (2004-2008), Kathmandu University, Nepal

Experience

  • Postdoctoral Research Fellow (2017-2019), Mayo Clinic, Rochester, United States.

1. Supported Mayo Clinic to established Immune monitoring core platform for oncolytic virus to run phase I clinical trials

2. Prepared NK cellular product for clinical application for Mayo Clinic

  • Scientist: Century Therapeutics (current position)
  • Developing off-the-shelf cellular therapies (CART, CARNK) for brain tumors


Dr Ashim Dhakal obtained his B. Tech degree in Electronics and Instrumentation Engineering from National Institute of Technology, Rourkela, India. With Erasmus Mundus Scholarship, Dr. Dhakal completed Masters in Photonics from University of St. Andres, Scotland, UK in 2011 and PhD in Photonics Engineering from University of Ghent, Belgium in 2016. After completing PhD, Dr. Dhakal returned back to Nepal with several prestigious grants such as EPSRC- Global Challenge Research Fund, TWAS and SIDA and founded the Phutung Research Institute (PRI) to work on optics/photonic based research in home country as a Principle Investigator.

During his tenure as a graduate student, Dr. Dhakal had served as a member of Educational Committee, European Masters in Photonics, Interuniversity Program (Ghent University, Free University Brussels, EPFL-Switzerland, TU-Denmark). Currently, he is a member of High-Level Committee for Implementation of National Science, Technology and Innovation Policy, Government of Nepal and also as a coordinator of the subcommittee: Promotion of Research and Development.


Dr Wang Di is a Plastic Surgeon at Plastic Surgery Hospital (Institute) of Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. He graduated from Peking Union Medical College, Tsinghua University, Beijing, China. His department is one of the most famous clinical centers for auricular diseases all over the world. Approx. 1/4 ear reconstruction surgeries around the world are done in his hospital. His clinical practices focus on ear reconstruction surgery and researches focus on auricular cartilage tissue-engineering and vascular tissue-engineering. He is currently a visiting scholar at Engineered Living System Laboratory (Shrike Zhang Lab) at Harvard Medical School where he is doing research in 3D bioprinting of vascular tissue scaffolds.


Dr Bishesh Khanal is a research scientist and chairperson of NAAMII, a recently established research institute in Nepal focusing on informatics, AI and applied mathematics. He is also a senior AI scientist at Fusemachines and visiting researcher at King’s College London. After completing his PhD from INRIA, Sophia Antipolis, France and Post-doctoral research at King’s College London and Imperial College London, he moved back to Nepal in January 2019. His key areas of interest include visual perception, machine learning and AI with special interest in applying them to identify problems relevant to low income countries and help develop innovative solutions, particularly in the field of medicine. He believes that the advancement in computational science and AI has provided a unique opportunity for resource constrained countries to explore exciting avenues of research by just using some computers and quality manpower.


Panelist:

Mrs Jyoti Acharya

Mrs Jyoti Acharya is a Joint Chief Medical Technologist and a microbiologist at Nepal Public Health Laboratory (NPHL), Teku, Kathmandu. Mrs. Acharya Started his career as the Head of the laboratory at Bhaktapur Hospital in 1995. Later she moved to the NPHL, first as a Senior medical technologist at Quality Control and Immunology/ JE Serology Department and later promoted as a chief Microbiologist.  During her tenure at NPHL, she was involved as a focal person in AMR Surveillance, a member secretary of Human Health Technical Working Group for AMR containment and the supervisor for JE/Measles/Rubella Serology National Reference Laboratory.

Mrs Acharya obtained her BSc MLT degree and MSc in Medical Laboratory Technology (Microbiology) from Maharjgunj Campus, Institute of Medicine, Tribhuvan University in 1990 and 2009, respectively. She has participated in several national and international conferences and workshops and authored many peer reviewed scientific papers. She was also the recipient of ASM student and post-doctoral travel awards for poster presentation at ASM Microbe Conference held at San Francisco, 2019, and Bill and Melinda Travel Awards for poster presentation at 21st International Pathogenic Neisseria Conference 2018, Monterey, California, 2018.

Mrs Acharya is also a Member Secretary of AMR Surveillance Technical Committee and a Working group member of GARP-Nepal (Global Antibiotic Resistance)


Dr Ajit Karna is a veterinarian, public health scientist, and microbiologist. Dr. Karna obtained his veterinary medical degree from Tribhuvan University, Institute of Agriculture and Animal Science, Chitwan in 2009. After working as a veterinary clinician for few years, he joined the University of New South Wales, Australia for master’s in public health and International Public Health. After completing his MPH/MIPH program in Australia, he moved to Colorado State University, the USA where he obtained a Ph.D. in Microbiology (Virology and Epidemiology) in 2017. He has then worked as a postdoctoral research scientist in the department of Biology and adjunct professor in the department of public health sciences at New Mexico State University. Dr. Karna is a member of the American Society of Tropical Medicine and Hygiene (ASTMH), American Society of Microbiology (ASM), Nepal Veterinary Association, and a life member of Nepal Veterinary Council. He was the recipient of the Australian Government Endeavour Award 2011, Australian Government Development Scholarship 2011, and Livestock-Climate Change Collaborative Support Program 2012. He has authored and co-authored number of peer-reviewed research papers on infectious diseases. His research interest is on infectious diseases in general and particularly zoonotic diseases. He is a founder of Open Lab LLC, USA through which is conducts consultancy services in research and development.

Currently, Dr. Karna holds the position of senior scientist at Center for Health and Disease studies Nepal and grantee of several national and international grants.


Moderators:

Dr Roshan Lal Shrestha is a Research Fellow at Department of Cancer Genetics, National Cancer Institute, NIH, USA.

Dr Shrestha completed BMLT degree from Manipal Academy of Higher Education, Manipal, India in 2003. After completing BMLT, he worked as a medical technologist in Om Hospital until 2007. Between 2003 to 2007, Dr. Shrestha also worked at Kathmandu Medical college Teaching Hospital, Unity Hospital and CIWEC Hospital as medical technologist. Besides, clinical job, Dr Shrestha also served as an assistant lecturer at Om Health Campus where he taught BSc Nursing and PBN students for one academic year.

In 2007 Dr Shrestha then moved to the UK and completed MSc. by Research in Medical Biosciences. He then moved to Department of Genetics at the University of Cambridge, first as a research assistant and later joined as a PhD student in the same department and completed PhD in 2015.

In 2015, Dr Shrestha received the post-doctoral fellowship and moved to the USA to join NCI, NIH, where he is continuing his tenure as a research fellow. His research interest is focused on aneuploid tumors and exploitation of aneuploid nature of cells as therapeutic tool.

He is also the founding member of Center for Health and Disease Studies-Nepal, based in Kathmandu. He is the lead for Research and Academics of Blood Transfusion Service Technology Transfer project, an initiative of NRN Academy.


Dr Sushila Maharjan is a research scholar at Brigham and Women’s Hospital at Harvard Medical School, USA. Her present research is focused on developing ‘organ-on-a-chip’ systems and 3D bio-printed tissue models to mimic human organs in vitro.

Before joining Harvard Medical School, she was a postdoc fellow at laboratory of Biomedical Polymers and Tissue Engineering at Seoul National University, Korea. Dr. Maharjan received her Ph.D. in Biochemistry from Sun Moon University, Korea, Master’s degree in Chemistry and Bachelor’s degree in Biological Sciences, both from Tribhuvan University, Nepal. She has extensive research experience in diverse fields including molecular biology and biotechnology, metabolic and genetic engineering, drug and vaccine delivery, and biomaterial and tissue engineering.

She has contributed over 40 articles in peer-reviewed international journals and 3 book chapters. Dr Maharjan’s exemplary achievements in research have been recognized by prestigious “Elsevier Foundation Awards for Early Career Women Scientists, 2016” and “Best Poster Award, Korean Society of Glycobiology 2011”. She has also received several fellowships and research grants including “American Fund for Alternatives to Animal Research fellowship 2016”, “Brain Korea 21 PLUS fellowship 2015”, TWAS Research Grants in Basic Sciences 2013,”, Korean Research Fund Scholarship 2007- 2010″, and Sun Moon University PhD fellowship 2006.

Dr Maharjan is also a co-founder of Research Institute for Bioscience and Biotechnology (RIBB) in Nepal. Besides, she is a member of the ‘Organization for Women in Science for the Developing World (OWSD)’ and TWAS (The World Academy of Sciences) Young Affiliate.

To register for this event please visit the following URL: http://knowledge.nrna.org/participate/ →

 

Date And Time

2020-10-11 @ 02:30 PM to
2020-10-11 @ 07:00 PM
 

Location

Online event

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